Jaundice Disease Essay Example

Jaundice Disease Essay The word jaundice is derived from a French word called as jaune, which means yellow. It is a very common condition which is seen in newborn babies which can be treated by exposing them to sunlight. It is also known as yellow skin or eyes disease. It turns your skin, mucous membranes, sclera (the white of your eyes) into a single yellow color. This yellow pigment which is seen on your skin is due to bilirubin which is a byproduct of old red blood cells. If you are affected by jaundice consider it to be a serious problem which cannot to be taken lightly. Nearly 1% red blood cells retire everyday and those are replaced by fresh blood cells. These old blood cells are processed in the liver and later disposed. If there happens to be too many old red blood cells the yellow pigment builds up in the body, which results in the first stages of jaundice. Even though jaundice is not a disease but it is a sign for many other diseases. Jaundice is very common among babies due to the immature functioning of the liver. It is not equipped to deal with the removal of bilirubin from the bloodstream. Jaundice occurs mainly due to liver failure but there are many other reasons by which it is affected. Bilirubin is a natural product arising from the normal breakdown of red blood cells in the body and is excreted in the bile, through the actions of the liver. Jaundice is most often the result of a disorder affecting the liver it can be caused by a variety of other conditions affecting for example the blood or spleen. It should be thoroughly investigated so that the underlying cause can be identified and treated. We will write a custom essay sample on Jaundice Disease specifically for you for only $16.38 $13.9/page Order now We will write a custom essay sample on Jaundice Disease specifically for you FOR ONLY $16.38 $13.9/page Hire Writer We will write a custom essay sample on Jaundice Disease specifically for you FOR ONLY $16.38 $13.9/page Hire Writer The red blood cells in our circulation carry oxygen to all parts of the body and have a life span of about 120 days. At the end of their life they are broken down and removed from the circulation by special cells called phagocytes, which are found within the bone marrow, spleen and liver. New red cells are of course continually manufactured and this also takes place within the bone marrow. Following breakdown of the red cells some of their component parts such as amino acids and iron can be re-used by the body. Other components such as bilirubin need to be removed. Knowing how this removal pathway works is the key to understanding how jaundice occurs. Most waste products of the body are excreted in the urine via the kidneys but the liver and bile system is the other main physical route out of the body for these substances. By waste products we mean the many compounds that arise in the course of the bodys metabolism but almost all forms of drugs must also be eliminated either via the urine or bile routes. In the case of bilirubin released from old red cells, it passes through the bloodstream to the liver, where the liver cells process it. These cells carry out many complex chemical functions and also produce the liquid bile, which is the vehicle by which the cells discharge their output to the bile duct system. This is a branching network of tiny tubes throughout the liver, which merge in the same way as the branches of a tree. Ultimately a single main bile duct comes out of the liver and joins the first part of the small intestine (duodenum). Bile (and therefore bilirubin) then passes out through the small and large intestines and is excreted in the stool (feces). Bile is green in colour, but bacteria in the large bowel act to change the bilirubin to substances that are brown, which gives stool its characteristic colour. Some of the bilirubin is reabsorbed back into the body through the bowel wall, eventually appearing in the urine as a substance called urobilinogen (although the typical yellow/orange colour of urine is in fact due a different pigment called urochrome). Therefore, any failure of the bilirubin removal pathway will lead to a build-up of bilirubin in the blood. When this happens the individuals skin turns yellow, causing jaundice. There are many conditions that could be associated with jaundice, such as: An excessive breakdown of red blood cells The balance between manufacture and breakdown of red cells is normally precisely balanced and equal but there are several conditions in which the rate of breakdown increases. If the amount of bilirubin thus released exceeds the livers capacity to remove it, then jaundice will develop. The medical term for excessive red cell breakdown is haemolysis, and within the developed world it is a fairly rare condition. Malaria is however a major cause in tropical climates as the malaria parasites live within the red cells and shorten their life. Similarly the condition in which a foetus develops haemolysis due to incompatibility of its Rhesus blood group with that of its mother is now rarely seen in the UK where we routinely check for Rhesus antibodies in the mothers blood. In parts of the world where antenatal care is not as good haemolytic disease of the newborn is much more common. A temporary jaundice of newborn babies is however quite common, due to the relative immaturity of the babys liver cells and the higher than normal rate of cell breakdown that occurs in the first few weeks of life. It improves rapidly without treatment although when too high it can be speeded up by exposing the baby to ultraviolet light. Jaundice of the newborn is commoner in premature babies as their liver is even more immature than a baby born at term. Autoimmune haemolytic anaemia is a rare disease in which the bodys immune system seems to attack the red cells. It usually affects adults. Haemolysis can also be a side effect of some drugs, eg dapsone. Impairment of liver cell function The commonest cause is a viral infection of the liver cells (hepatitis). Many different types of infection including glandular fever (mononucleosis) can also be responsible for this. Alcohol abuse and subsequent scarring of the liver (cirrhosis) can cause significant cell damage leading to jaundice. Other less common conditions causing liver cell damage include haemochromatosis, alpha-1 antitrypsin deficiency and primary biliary cirrhosis. Tumours of the liver either primary liver cancers (arising from the liver tissue itself) or more commonly, the secondary spread of a tumour from elsewhere in the body into the liver can lead to cell failure and jaundice. Blockage of the bile ducts This can occur as a result of abnormality inside or outside the ducts. The commonest example of an internal blockage is a gallstone. Tumours of the bile duct are rare but if large enough, or situated just where the bile duct meets the duodenum, then they can block the flow of bile. At this junction point, known as the ampulla of Vater, the tube from the pancreas gland also joins to the duodenum. Cancer of the pancreas tends to arise in the part of the pancreas nearest to the ampulla of Vater, so is another potential cause of obstructive jaundice. Any external organ or mass lying nearby that becomes large enough to press on the bile duct could be responsible. Examples include swollen internal lymph glands, a cyst (perhaps of the pancreas) or scar tissue following a previous infection or surgery. Symptoms of Jaundice, other than that of the jaundice itself, will relate to the underlying cause. For example someone with haemolysis might also be anaemic and tired. If a gallstone were responsible there would probably have been a preceding history of pain in the abdomen. A cancer might be accompanied by weight loss, and so on. When jaundice is due to obstruction of the bile duct the person will often notice that their urine becomes dark and stools become pale, as the excess bilirubin spills over into the urine and no longer colours the stool. Obstructive jaundice is also often accompanied by intense itching. The diagnosis is made by recognition of the patients appearance and accompanying symptoms. A blood test will confirm the raised bilirubin level and other tests such as those for hepatitis and haemolysis are also done on the blood. Ultrasound is a good way to inspect the liver and bile ducts for signs of obstruction, and often can give useful information on the pancreas gland. CT scanning also helps diagnose obstructive jaundice accurately. Treatment will depend upon the diagnosis behind the symptom of jaundice. For example, if the problem is one of gallstones, then removal of the gallbladder may be required. Jaundice comes in several other types, I will elaborate briefly about some of those types as follows: Neonatal jaundice is usually harmless: this condition is often seen in infants around the second day after birth, lasting until day 8 in normal births, or to around day 14 in premature births. Serum bilirubin normally drops to a low level without any intervention required: the jaundice is presumably a consequence of metabolic and physiological adjustments after birth. In extreme cases, a brain-damaging condition known as kernicterus can occur; there are concerns that this condition has been rising in recent years due to inadequate detection and treatment of neonatal hyperbilirubinemia. Neonatal jaundice is a risk factor for hearing loss. Jaundiced eye, It was once believed persons suffering from the medical condition jaundice saw everything as yellow. By extension, the jaundiced eye came to mean a prejudiced view, usually rather negative or critical. Alexander Pope, in An Essay on Criticism (1711), wrote: All seems infected that the infected spy, As all looks yellow to the jaundiced eye. Similarly in the mid 19th century the English poet Lord Alfred Tennyson wrote in the poem Locksley Hall: So I triumphed ere my passion sweeping thro me left me dry, left me with the palsied heart, and left me with a jaundiced eye. In conclusion, if you or one of your friends or relatives suspect that you may have jaundice, it is essential that you arrange to see your doctor in order that the underlying cause is identified and any possible treatment initiated as soon as possible.

ITCs cigarette Business Essay Example

ITCs cigarette Business Essay Example ITCs cigarette Business Essay ITCs cigarette Business Essay High incidence of taxation continuously has been a deterrent to ITCs cigarette Business. Taxes amount to over 80% of the value added in the cigarette industry, hence making cigarettes increasingly unaffordable to the Indian tobacco consumer. There are about 200 million tobacco consumers in India, and of them, fewer than 14% can afford cigarettes, although cigarettes contributes 90% of total Central and State revenues generated from tobacco sector. Non-cigarette forms of tobacco consumption, constituting nearly 85% of tobacco consumption in the country, contribute barely 10% of Government revenues because of the difficulty of tax collection and the low tax yields that characterize this largely unorganized sector. There has been a prolonged punitive and discriminatory taxation regime at Central and State levels have made cigarettes unaffordable to the majority of tobacco consumers. Also, Non-cigarette forms of tobacco products are largely produced in the unorganized sector characterized by lower rates of tax and ineffective enforcement. As a result, there is a growing migration to lower value forms of tobacco consumption. Just to illustrate, in 2003, the effective excise duty on most tobacco products other than cigarettes is equivalent to about 12% of the net value of the product whereas on cigarettes this component is as high as 140%. Moreover in 2003, VAT was introduced on cigarettes already subject to a plethora of taxes. The export prospects were affected by the uncertainty and diminished market presence caused by the crop holidays in Andhra Pradesh. As a result, the export attractiveness of Indian tobaccos is caught up in a vicious cycle to the growing detriment of the tobacco farmers. Also, small base of domestic cigarette consumption discourages investment in RD and quality enhancement of tobacco varieties thereby sub-optimizing the export potential of tobacco. There was also threat from contraband trade of cigarettes aided with loopholes in the regulatory framework and lack of effective enforcement. In 2004-05, severe restrictions were imposed on the cigarettes industry with respect to advertisement, sale and consumption of tobacco products with the implementation of the Cigarettes and Other Tobacco Products (Prohibition of Advertisement and Regulation of Trade, Commerce, Production, Supply and Distribution) Act, 2003 (COTPA). All these in totality made cigarette business less profitable and more challenging. As a result, ITC started diversifying into multiple businesses. While exploring new opportunities, for long term growth, ITC depended on its multiple strengths synergies that it could bring about from its existing businesses. We discuss few of such businesses in detail in the following sections. The mill at Bhadrachalam produces 240,000 TPY of papers and boards and has three board machines and two smaller paper machines. The mill produces paperboards for the packaging and graphics segments with a product range that includes Cyber XLPac (folding box boards), Pearl/Saphire Graphik (solid bleached boards) high value boards and the Ecoviron range of recycled boards. It also makes liquid packaging boards for Tetrapak in India. One of the big innovations at this mill has been the commissioning of an Elemental Chlorine Free (ECF) fibre line. This is a state-of-the-art line which meets the effluent norms set by the Ministry of Environment and Forests of the Government of India and thus ties in with the Environment theme in its Triple Bottomline. The Tribeni Tissues unit was initially part of the Wiggins Teape Company, UK from 1961 to 1988. In 1992, it merged with ITC Ltd. The mill and its paper machines were refurbished with the latest technology. It has a capacity of 33,000 TPY with a product range that includes cigarette tissues, fine papers, packaging papers and specialties. The range from papers produced is quite diverse including Cigarette Tissues and Components, Laminating Base Tissue, Acid-Free and Anti-Rust Tissues, Low Grammage Printing Papers, Di cor Papers to Insulation Grade and Medical Grade Papers. The unit is ISO 9001:2000 version and ISO 14001 accredited. ITC has another paperboard facility at Coimbatore, Tamil Nadu which was acquired from BILT Industrial Packaging Company in 2004. This mill manufactures Coated Duplex boards Greyback and Whiteback made with 100% recycled materials and has a single board machine with 90,000 TPY of capacity. The products are continuously monitored for quality using a Siemens DCS system and Measurex QCS system. Quality as in other ITC units is a big focus and the mill has continuously demonstrated quality having achieved ISO 9001, ISO 14001 and OHSAS 18001 certifications. The delivery of rolls and sheets is ensured by a modern Finishing House with short turnaround times. Eco Naturo and Eco Naturo-HS are the two grades of Coated Duplex Grey Back board made from this unit. For almost the first time in India, a customer has the option to buy a higher bulk and stiffness of Greyback Board (GD2 grade) for his carton requirements. The unit at Bollarum near Hyderabad produces 5000 TPY of Cast Coated Papers and Boards, 10,000 TPY of Poly Extrusion coated boards and 10000 TPY of C2S art boards and Ivory cards. It is the market leader in South Asia in carton boards and ranks second in turnover within the Indian paper industry. Most leading Fast Moving Consumer Goods Brands in India use paperboard manufactured at this location. Exports constitute about 20% of sales and cater to international markets in Malaysia, Sri Lanka, Bangladesh, Iran, Australia, UAE, Turkey, China, Singapore, UK, Greece, Germany and USA. The unit is ISO 9001:2000 series accredited.

The Dark Side of Literature Essay Example | Topics and Well Written Essays - 1500 words

The Dark Side of Literature - Essay Example "London" is a short poem of four stanzas in which Blake laments the fact that "marks of weakness, marks of woe" can be seen in every face he meets in the city. In "every cry of every Man", in the "Infant's cry of fear", and in every other voice, the freedom-loving poet hears the "mind-forg'd manacles." The poet makes a specific attack on the twin arms of power-the Church and the Crown: Plainly, the poet is of the view that the blight has entered into the very heart of the London, for harlots are used and abused not by the high and mighty alone, but by every man who thinks he can get his money's worth from them-be the sum a few pence or more than a few guineas. It is the curse of the harlot that engenders the "Infant's cry of fear" and makes marriage a farce that begins and ends as a hearse that transports men and women from the plagues of Earth to the plagues of Hell. If "London" appears dark, "The Human Abstract" is quite unrelentingly, black in its round and full condemnation of the 'Human Brain'-not just the brain of politician or monarch or demagogue, but the human brain. The poet reveals the selfish foundation of even seemingly benevolent emotions such as 'Pity' and 'Mercy': Pity would be no more If we did not make somebody Poor; And Mercy no more could be If all were as happy as we. In such a context, it is only "mutual fear" that brings peace till selfishness waxes too great. Then, "Cruelty knits a snare/And spreads his baits with care." "Holy fears" soon "water...the ground with tears." This is all that it takes for "Humility" to take root beneath the cruel foot. The "dismal shade/ of Mystery" then drops over his head and "the Catterpiller and Fly/ Feed on the Mystery." The fruit of this tree appears "Ruddy and sweet to eat" but it has a canker at its core and it is the "fruit of Deceit." The Gods of earth and sea may search for this tree and its fruit through all Nature, but the search would be "in vain" for the tree grows not in Nature, but in Man-"in the Human Brain." If in "London" Blake had seemed to sympathize with "Chimney sweeper", with "hapless soldier" or "youthful Harlot", in "The Human Abstract" the poison tree is revealed as one that can flourish in any human brain. While the oppression of Church and the State will be condemned and rightly so, the poet's task is not to be populist or to strive to be popular-he has to shine the light of his poetry into the cracks and crevices of every human heart and soul and brain. This should lead to a transformation-but such a change can occur only if the need for change is manifest, and that, surely, is what a poet like Blake is trying to achieve. In